Protein Modification Reagents
Medchemexpress LLC N3-PEG4-C2-NHS ester | 944251-24-5 | 98.9% | 250 MG
N3-PEG4-C2-NHS ester is a non-cleavable 4-unit PEG linker used in the synthesis of antibody-drug conjugates (ADCs). It acts as a click chemistry reagent, possessing an Azide group that facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions with alkyne-containing molecules. It also participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. This product is intended exclusively for research purposes.
- Non-cleavable 4-unit PEG linker
- Used in synthesis of antibody-drug conjugates (ADCs)
- Functions as a click chemistry reagent with an Azide group
- Facilitates copper-catalyzed azide-alkyne cycloaddition (CuAAc) reactions
- Participates in strain-promoted alkyne-azide cycloaddition (SPAAC) reactions
- Intended exclusively for research purposes
Cayman Chemical dG-PEG 2000 250mg
A PEGylated derivative of DSG; LNPs containing DSG-mPEG(2000) and encapsulating an imidazoquinoline TLR7 and TLR8 agonist and a peptide antigen EAch conjugated to PGA increase the activation of dendritic cells, macrophages, and B cells in the draining lymph node and dendritic cells and B cells in the spleen in mice compared to the non-LNP-encapsulated PGA-conjugated TLR7/8 agonist and peptide antigen.
Medchemexpress LLC Tos-PEG4-NH-Boc (PROTAC linker 7) | 1246999-33-6 | ≥98.0% | 5 G
Tos-PEG4-NH-Boc (PROTAC Linker 7) is a PEG-based PROTAC linker used in the synthesis of PROTACs. This product is intended for research use only. PROTACs are compounds with two ligands joined by a linker; one targets an E3 ubiquitin ligase, and the other targets a specific protein. They leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Intended for research use only
- Targets an E3 ubiquitin ligase and a specific protein
- Leverages the ubiquitin-proteasome system
- Selectively degrades target proteins
eMolecules 1393330-40-9 | Propargyl-PEG5-NHS ester | Broadpharm | MFCD22574798 | 401.412 | C18H27NO9 | 98.000 | O=C(CCOCCOCCOCCOCCOCC#C)ON1C(=O)CCC1=O | 100mg | 229582898
Propargyl-PEG5-NHS ester | Broadpharm | 1393330-40-9 | MFCD22574798 | 401.412 | C18H27NO9 | 98.000 | O=C(CCOCCOCCOCCOCCOCC#C)ON1C(=O)CCC1=O | 100mg | 229582898
Medchemexpress LLC Fluorescein-PEG4-acid | 1807518-76-8 | MFCD23726637 | 95.0% | 654.68 g/mol | C32H34N2O11S | 5 MG
Fluorescein-PEG4-acid is a PEG-based linker that incorporates a fluorescein dye and terminates in a free carboxylic acid. It is intended for use as a linker in PROTAC synthesis and for covalent conjugation to biomolecules to provide fluorescent labeling for assays and imaging.
- PEG4 spacer with a fluorescein dye for fluorescence tagging.
- Terminal carboxylic acid enables amide coupling to amines.
- Suitable as a PROTAC linker and for fluorescent labeling applications.
- Yellow to orange solid; molecular weight 654.68 g/mol.
- Store under nitrogen, away from moisture; in solvent: -80°C (up to 6 months), -20°C (up to 1 month).
Soltec Ventures Inc Tris(2-carboxyethyl)phosphine hydrochloride | 51805-45-9 | MFCD00145469
Tris(2-carboxyethyl)phosphine hydrochloride | Mol Wt: 286.65 | 51805-45-9 | MFCD00145469
eMolecules DBCO-PEG8-Maleimide | Broadpharm |850.963 | C44H58N4O13 | 0.000 | O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O)NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 25mg | 686678581
DBCO-PEG8-Maleimide | Broadpharm |850.963 | C44H58N4O13 | 0.000 | O=C(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O)NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 25mg | 686678581
eMolecules DBCO-PEG6-Maleimide | Broadpharm |762.857 | C40H50N4O11 | 0.000 | O=C(CCOCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O)NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 25mg | 686678577
DBCO-PEG6-Maleimide | Broadpharm |762.857 | C40H50N4O11 | 0.000 | O=C(CCOCCOCCOCCOCCOCCOCCNC(=O)CCN1C(=O)C=CC1=O)NCCC(=O)N1Cc2ccccc2C#Cc2ccccc12 | 25mg | 686678577